1 Flying from La Paz to Rurrenabaque
This short, low-altitude hop from Andes to Amazon has to be one of the best-value, dollar for dollar, in the world; feel your chin hit the floor as savage pinnacles and blinding icefields loom within touching distance, falling away to the infinite expanse of green that first shocked and awed the conquistadors.
Set deep in pristine Amazonian rainforest and owned by the local indigenous Tacana community, the Albergue Ecologico Chalalán is the ideal place to explore Parque Nacional Madidi, and a model of how ecotourism ought to be.
3 San Ignacio de Moxos
Quite possibly the friendliest village in all South America, with unique flute and drum music, a famous July fiesta and a historic, candle-lit Jesuit church.
4 Río Mamoré
Sling your hammock up and relax on a slow boat down this mighty wilderness river between Trinidad and the Brazilian frontier.
5 Reserva Manuripi
Get way off the beaten track in the Bolivian Amazon’s northernmost reserve, a pristine stretch of rainforest that supplies the bulk of the world’s Brazil nuts.