From Guadalajara, the most direct route to Mexico City heads through the major junction of La Piedad and continues east towards Irapuato. If you can afford to dawdle a while, though, it’s infinitely more rewarding to follow the slower, southern road through Zamora and Morelia, spending a couple of days in Uruapan and Pátzcuaro. From Uruapan, Hwy-37 slices south through the mountains to the Pacific coast at Lázaro Cárdenas.

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  • Uruapan
  • Paricutín
  • Pátzcuaro