Italy’s largest modern-art museum, the Museo di Arte Moderna e Contemporanea (MART) was designed by Mario Botta and opened in December 2002. The spectacular building, with spacious galleries wrapping themselves around a central circular atrium flooded with light, is impressive enough before you view the art inside. Skilfully curated, themed exhibitions use works loaned from institutions and individuals around the world as well as drawing on the gallery’s collection of 30,000 paintings, design pieces and sculptures by big-hitting names including Lichtenstein, Rauschenberg and Warhol (as well as lesser-known locals such as Italian Futurist Fortunato Depero, Giorgio de Chirico and Giorgio Morandi). At least four large shows run at any one time and previous installations have covered Postmodernism, futuristic car design, Schiele, Klimt and Kokoschka, and Alice in Wonderland in art and design. Allow at least three hours to see everything.