The Soutpansberg, an impressive range of hills, particularly when approached from the south, attracts sufficient rainfall to create a subtropical climate, and spectacularly lush farms along the southern slopes produce a range of exotic crops such as avocados and macadamia nuts. In other parts, the rocky kloofs and green hillsides offer unspoilt mountain retreats, shaded by up to 580 different species of tree, and the home of monkeys, small antelopes, warthogs and some raptors. The uniqueness of the area led to it being designated a UNESCO Biosphere Reserve in 2009, with a similar protection and development status as the Waterberg Biosphere Reserve.
The N1 highway bisects the range, passing through missable Makhado, situated in the southern shadow of the mountains, then climbing over a low pass and descending through a pair of tunnels on the northern side. Once over the escarpment, the highway runs north across mostly empty baobab plains to Musina and the Limpopo River.